Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium

Abstract Background COL4A1 defects are known to cause a variety of multisystem disorders with significant vascular dysfunction leading to neuronal damage. Case reports suggest that patients with COL4A1 mutations or extracellular COL4A1 deficiency in the basement membrane may put individuals at incre...

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Autori principali:	Pratheepa Kumari Rasiah, Kumar Abhiram Jha, Jordy Gentry, Nobel A. Del Mar, Lawrence M. Pfeffer, Anton Reiner, Rajashekhar Gangaraju
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-12-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Traumatic brain injury VE-cadherin GFAP Microglia Endothelial Vision
Accesso online:	https://doi.org/10.1186/s13287-025-04804-6
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