Activation of the G-protein coupled estrogen receptor 1 (GPER1) reduces transient receptor potential vanilloid 1 (TRPV1) activity and human iPSC-derived nociceptive neuron firing

Abstract Chronic pain affects approximately one fifth of people worldwide and displays a huge burden for health care institutions. Some chronic pain conditions have a higher prevalence in women than men. Previous studies related these sex-specific differences to sex-hormone receptor activation and i...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Oliver Dräger, Angelique Grell, Asaria E. Vogel, Erhard Wischmeyer, Beatrice A. Nossek
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2026-07-01
Цуврал:	Stem Cell Research & Therapy
Нөхцлүүд:	iPSC Nociceptors Neuronal differentiation GPER1 TRPV1 TRESK
Онлайн хандалт:	https://doi.org/10.1186/s13287-026-05174-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!