Unbiased assessment of 2-arachidonoylglycerol in cardiovascular inflammation

Abstract 2-arachidonoylglycerol (2-AG) is an endogenous modulator of inflammatory processes. Recent studies demonstrate its key role in inflammatory cardiovascular diseases, such as atherosclerosis and left ventricular remodelling. However, whether 2-AG acts as a pro- or anti-inflammatory agent in c...

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Autori principali:	Moritz Nöthel, Franziska Dorer, Alexandru Odainic, Carolyn Krause, Marie Rüthing, Jasper Spitzer, Ulrike Strube, Theresia Weise, Dieter Lütjohann, Georg Nickenig, Susanne V. Schmidt, Julian Jehle
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Soggetti:	2-arachidonoylglycerol Endocannabinoid system Monocytes Inflammation Coronary heart disease Acute coronary syndrome
Accesso online:	https://doi.org/10.1038/s41598-025-28969-5
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