Low-dose tamoxifen treatment reduces collagen organisation indicative of tissue stiffness in the normal breast: results from the KARISMA randomised controlled trial

Abstract Background Tissue stiffness, dictated by organisation of interstitial fibrillar collagens, increases breast cancer risk and contributes to cancer progression. Tamoxifen is a standard treatment for receptor-positive breast cancer and is also aproved for primary prevention. We investigated th...

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Autores principales:	Sara Göransson, Pablo Hernández-Varas, Mattias Hammarström, Roxanna Hellgren, Magnus Bäcklund, Kristina Lång, Ann H. Rosendahl, Mikael Eriksson, Signe Borgquist, Staffan Strömblad, Kamila Czene, Per Hall, Marike Gabrielson
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-11-01
Colección:	Breast Cancer Research
Acceso en línea:	https://doi.org/10.1186/s13058-024-01919-1
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