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Is the tumor cell side of the immunological synapse a polarized secretory domain?

The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While significant attention has been focused on the lymphocyte side of the IS, particularly its role as a secretory domain for lytic granules, the...

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Hlavní autoři: Andrea Michela Biolato, Liza Filali, Diogo Pereira Fernandes, Flora Moreau, Takouhie Mgrditchian, Céline Hoffmann, Clément Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-09-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1452810/full
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