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Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel

Background: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and have also been implicated in chemotherapy resi...

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Principais autores: Mariana Feijó, Lara R. S. Fonseca, Gonçalo Catarro, Cátia V. Vaz, Carlos Rabaça, Bruno J. Pereira, Eugenia Gallardo, Endre Kiss-Toth, Sara Correia, Sílvia Socorro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Medical Sciences
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Online adgang:https://www.mdpi.com/2076-3271/13/4/322
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