A novel V236I substitution in the β-tubulin isotype 1 gene of Ancylostoma ceylanicum is associated with reduced in silico benzimidazole-binding affinity

Background and Aim: Benzimidazoles (BZ) remain the cornerstone of soil-transmitted helminth control programs; however, the emergence of resistance-associated mutations in the β-tubulin gene threatens their long-term effectiveness. Information on BZ resistance markers in hookworms from Southeast Asia...

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Principais autores:	Jan Clyden B. Tenorio, Ian Kim B. Tabios, Jose Ma. M. Angeles, Maria Mardalena Martini Kaisar, Mark Andrian B. Macalalad, Fredmoore L. Orosco, Prasert Saichua, Sutas Suttiprapa
Formato:	Artigo
Idioma:	Inglês
Publicado:	Veterinary World 2026-07-01
Series:	International Journal of One Health
Assuntos:	albendazole ancylostoma ceylanicum benzimidazole resistance β-tubulin hookworm molecular dynamics soil-transmitted helminths southeast asia
Acceso en liña:	https://onehealthjournal.org/Vol.12/No.2/1.pdf
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