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Development of a β-glucosidase improved for glucose retroinhibition for cellulosic ethanol production: an integrated bioinformatics and genetic engineering approach

Abstract Background The global energy crisis, driven by economic growth and the increasing demand for energy, highlights the urgency of searching for alternative energy sources to mitigate environmental pollution and climate change. β-Glucosidases act in the final step of the enzymatic hydrolysis of...

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Principais autores: Raíza dos Santos Azevedo, Hugo Santana, Vinícius Rosa Seus, Alex Dias Camargo, Adriano Velasque Werhli, Karina dos Santos Machado, Letícia Jungmann Cançado, Betania Ferraz Quirino, Luis Fernando Marins
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-04-01
Serier:Biotechnology for Biofuels and Bioproducts
Fag:
Cellulases
Molecular docking
Genetic manipulation
Competitive inhibition
Catalytic activity
Lignocellulosic biomass
Online adgang:https://doi.org/10.1186/s13068-025-02643-4
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