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Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma.

MYCN is a transcription factor that is expressed during the development of the neural crest and its dysregulation plays a major role in the pathogenesis of pediatric cancers such as neuroblastoma, medulloblastoma and rhabdomyosarcoma. MeCP2 is a CpG methyl binding protein which has been associated w...

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Detalhes bibliográficos
Principais autores: Derek M Murphy, Patrick G Buckley, Sudipto Das, Karen M Watters, Kenneth Bryan, Raymond L Stallings
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3120883?pdf=render
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