G Protein-Coupled Receptor Kinase 2 as Novel Therapeutic Target in Fibrotic Diseases

G protein-coupled receptor kinase 2 (GRK2), an important subtype of GRKs, specifically phosphorylates agonist-activated G protein-coupled receptors (GPCRs). Besides, current research confirms that it participates in multiple regulation of diverse cells via a non-phosphorylated pathway, including int...

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Hauptverfasser:	Nan Li, Shan Shan, Xiu-Qin Li, Ting-Ting Chen, Meng Qi, Sheng-Nan Zhang, Zi-Ying Wang, Ling-Ling Zhang, Wei Wei, Wu-Yi Sun
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2022-01-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	G protein-coupled receptor kinase 2 (GRK2) G protein-coupled receptors fibrosis phosphorylation ECM - extracellular matrix
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.822345/full
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