Astroglial Kir4.1 potassium channel deficit drives neuronal hyperexcitability and behavioral defects in Fragile X syndrome mouse model

Abstract Fragile X syndrome (FXS) is an inherited form of intellectual disability caused by the loss of the mRNA-binding fragile X mental retardation protein (FMRP). FXS is characterized by neuronal hyperexcitability and behavioral defects, however the mechanisms underlying these critical dysfunctio...

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Bibliografiska uppgifter

Huvudupphov:	Danijela Bataveljic, Helena Pivonkova, Vidian de Concini, Betty Hébert, Pascal Ezan, Sylvain Briault, Alexis-Pierre Bemelmans, Jacques Pichon, Arnaud Menuet, Nathalie Rouach
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Nature Portfolio 2024-04-01
Serie:	Nature Communications
Länkar:	https://doi.org/10.1038/s41467-024-47681-y
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