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The role of aggrecan in normal and osteoarthritic cartilage

Abstract Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads. It is present in the extracellular matrix in the form of proteoglycan aggregates, in which many aggrecan molecules...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Peter J Roughley, John S Mort
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2014-01-01
Schriftenreihe:Journal of Experimental Orthopaedics
Schlagworte:
Online-Zugang:https://doi.org/10.1186/s40634-014-0008-7
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