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Endothelin type A receptors mediate pain in a mouse model of sickle cell disease

Sickle cell disease is associated with acute painful episodes and chronic intractable pain. Endothelin-1, a known pain inducer, is elevated in the blood plasma of both sickle cell patients and mouse models of sickle cell disease. We show here that the levels of endothelin-1 and its endothelin type A...

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Autori principali: Brianna Marie Lutz, Shaogen Wu, Xiyao Gu, Fidelis E. Atianjoh, Zhen Li, Brandon M. Fox, David M. Pollock, Yuan-Xiang Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2018-07-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/8516
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