Inhibition of monoacylglycerol lipase mediates a cannabinoid 1-receptor dependent delay of kindling progression in mice

Endocannabinoids, including 2-arachidonoylglycerol (2-AG), activate presynaptic cannabinoid type 1 receptors (CB1R) on inhibitory and excitatory neurons, resulting in a decreased release of neurotransmitters. The event-specific activation of the endocannabinoid system by inhibition of the endocannab...

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Autors principals:	E.L. von Rüden, R.M. Bogdanovic, C.T. Wotjak, H. Potschka
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2015-05-01
Col·lecció:	Neurobiology of Disease
Matèries:	Epileptogenesis Endocannabinoid system Fatty acid amide hydrolase FAAH Anandamide
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0969996115000881
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