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Computational identification and analysis of CNP0269688 as a natural product inhibitor disrupting the interaction between the HIV matrix domain and tRNA

Our research is dedicated to combating HIV by targeting its Matrix (MA) domain, which is crucial for viral assembly and replication. This strategy specifically aims to interrupt early-stage infection and deter drug resistance by focusing on this essential domain. Due to the MA domain’s conservation...

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Opis bibliograficzny
Główni autorzy: Chengjie Xu, Songtao Wu, Pengju Liu, Yao Huang, Yuchao Chen, Guoping Ding, Shengnan Jia
Format: Artigo
Język:Inglês
Wydane: Frontiers Media S.A. 2024-09-01
Seria:Frontiers in Chemistry
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Dostęp online:https://www.frontiersin.org/articles/10.3389/fchem.2024.1450339/full
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