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Intratumoral and peritumoral radiomics for the pretreatment prediction of response to neoadjuvant chemotherapy in rhabdomyosarcoma: a multicenter retrospective cohort study

Abstract Background Pediatric rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma in children, exhibits heterogeneous responses to neoadjuvant chemotherapy (NAC), necessitating reliable biomarkers for early prediction. This multicenter study evaluates MRI-derived radiomic features of intratu...

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Principais autores: Ge Zhang, Yun Peng, Yan Su, Lin Mei, Jugao Fang, Yuanhu Liu, Huanming Wang, Hongcheng Song, Dong Guo, Guoxia Yu, Shengcai Wang, Xin Ni
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-01-01
Serier:Insights into Imaging
Fag:
Pediatric rhabdomyosarcoma
MRI radiomics
Peritumoral
Neoadjuvant chemotherapy response prediction
Online adgang:https://doi.org/10.1186/s13244-025-02178-0
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