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Conservation and Enhanced Binding of SARS-CoV-2 Omicron Spike Protein to Coreceptor Neuropilin-1 Predicted by Docking Analysis

The Omicron variant of SARS-CoV-2 bears peptide sequence alterations that correlate with a higher infectivity than was observed in the original SARS-CoV-2 isolated from Wuhan, China. We analyzed the CendR motif of spike protein and performed in silico molecular docking with neuropilin-1 (Nrp1), a re...

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Principais autores: Piyush Baindara, Dinata Roy, Santi M. Mandal, Adam G. Schrum
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2022-03-01
Serija:Infectious Disease Reports
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Online dostop:https://www.mdpi.com/2036-7449/14/2/29
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