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Cheminformatics analysis of chemicals that increase estrogen and progesterone synthesis for a breast cancer hazard assessment

Abstract Factors that increase estrogen or progesterone (P4) action are well-established as increasing breast cancer risk, and many first-line treatments to prevent breast cancer recurrence work by blocking estrogen synthesis or action. In previous work, using data from an in vitro steroidogenesis a...

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Hlavní autoři: Alexandre Borrel, Ruthann A. Rudel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2022-11-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-022-24889-w
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