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TRIMming down Mycobacterium tuberculosis replication: TRIM32 is required for bacterial ubiquitination and autophagy induction in macrophages

Mycobacterium tuberculosis (Mtb) promotes its intracellular persistence by subverting defense mechanisms, such as autophagy. Remarkably, enhancing autophagy is sufficient to trigger intracellular Mtb killing and effective immune response, making this process a valid target of host-directed therapies...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Alessandra Romagnoli, Martina Di Rienzo, Mauro Piacentini, Gian Maria Fimia
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2023-12-01
Rangatū:Autophagy Reports
Ngā marau:
Urunga tuihono:https://www.tandfonline.com/doi/10.1080/27694127.2023.2278120
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