Comparative proteomic analyses demonstrate enhanced Interferon and STAT-1 activation in reovirus T3D-infected HeLa cells

As obligate intracellular parasites, viruses are exclusively and intimately dependent upon their host cells for replication. During replication viruses induce profound changes within cells, including: induction of signaling pathways, morphological changes, and cell death. Many such cellular perturba...

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Principais autores:	Peyman eEzzati, Krysten eKomher, Giulia eSeverini, Kevin eCoombs
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2015-04-01
Series:	Frontiers in Cellular and Infection Microbiology
Assuntos:	Mass Spectrometry RNA Viruses bioinformatics Cell signaling Liquid Chromatography Host cell alterations
Acceso en liña:	http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00030/full
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