Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

Abstract Background Maternal malaria is a tropical scourge associated with poor pregnancy outcomes. Women become resistant to Plasmodium falciparum pregnancy malaria as they acquire antibodies to the variant surface antigen VAR2CSA, a leading vaccine candidate. Because malaria infection may increase...

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Autori principali:	Michal Fried, Jonathan D. Kurtis, Bruce Swihart, Robert Morrison, Sunthorn Pond-Tor, Amadou Barry, Youssoufa Sidibe, Sekouba Keita, Almahamoudou Mahamar, Naissem Andemel, Oumar Attaher, Adama B. Dembele, Kadidia B. Cisse, Bacary S. Diarra, Moussa B. Kanoute, David L. Narum, Alassane Dicko, Patrick E. Duffy
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2018-03-01
Serie:	Malaria Journal
Soggetti:	Placental malaria VAR2CSA Birth weight Pregnancy loss Preterm delivery Anaemia
Accesso online:	http://link.springer.com/article/10.1186/s12936-018-2258-9
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