Immunization route-mediated differences in long-term maturation of humoral immune response induced by adenovirus vector-based COVID-19 vaccine Sputnik V in nonhuman primates

IntroductionOn the background of kaleidoscopic changes of SARS-CoV-2 circulating variants, constant presence of SARS-CoV-2 in the human population hampers the dissection of native long-term immunogenicity of COVID-19 vaccines.MethodsFor this purpose, we performed a more than two-year-long evaluation...

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Autors principals:	Amir I. Tukhvatulin, Ilya V. Gordeychuk, Alina S. Dzharullaeva, Inna V. Dolzhikova, Ekaterina O. Bayurova, Fatima M. Izhaeva, Anna V. Kovyrshina, Alla S. Zhitkevich, Daria V. Avdoshina, Stanislav A. Gulyaev, Tatiana V. Gulyaeva, Andrey V. Moroz, Ilias B. Esmagambetov, Ilya D. Zorkov, Anna A. Iliukhina, Artem Y. Shelkov, Alina S. Erokhova, Dmitry V. Shcheblyakov, Olga V. Zubkova, Aydar A. Ishmukhametov, Denis Y. Logunov, Alexander L. Gintsburg
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-09-01
Col·lecció:	Frontiers in Immunology
Matèries:	COVID-19 SARS-CoV-2 Sputnik V vaccine common marmosets serum maturation long-term immunogenicity
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1634187/full
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