On the underlying assumptions of threshold Boolean networks as a model for genetic regulatory network behavior

Boolean networks (BoN) are relatively simple and interpretable models of gene regulatorynetworks. Specifying these models with fewer parameters while retaining their ability to describe complex regulatory relationships is an ongoing methodological challenge. Additionally, extending these models to i...

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Autori principali:	Van eTran, Matthew Nicholson McCall, Helene eMcMurray, Anthony eAlmudevar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2013-12-01
Serie:	Frontiers in Genetics
Soggetti:	steady state attractor genetic regulatory network Boolean network state augmentation feedback loop
Accesso online:	http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00263/full
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