Evolution of the conformational dynamics of the molecular chaperone Hsp90

Abstract Hsp90 is a molecular chaperone of central importance for protein homeostasis in the cytosol of eukaryotic cells, with key functional and structural traits conserved from yeast to man. During evolution, Hsp90 has gained additional functional importance, leading to an increased number of inte...

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Principais autores:	Stefan Riedl, Ecenaz Bilgen, Ganesh Agam, Viivi Hirvonen, Alexander Jussupow, Franziska Tippl, Maximilian Riedl, Andreas Maier, Christian F. W. Becker, Ville R. I. Kaila, Don C. Lamb, Johannes Buchner
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2024-10-01
Serija:	Nature Communications
Online dostop:	https://doi.org/10.1038/s41467-024-52995-y
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