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The helical domain of the EcoR124I motor subunit participates in ATPase activity and dsDNA translocation

Type I restriction-modification enzymes are multisubunit, multifunctional molecular machines that recognize specific DNA target sequences, and their multisubunit organization underlies their multifunctionality. EcoR124I is the archetype of Type I restriction-modification family IC and is composed of...

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Principais autores: Vitali Bialevich, Dhiraj Sinha, Katsiaryna Shamayeva, Alena Guzanova, David Řeha, Eva Csefalvay, Jannette Carey, Marie Weiserova, Rüdiger H. Ettrich
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2017-01-01
Serier:PeerJ
Fag:
E. coli
Multisubunit enzyme complex
Molecular modeling
Domain interactions
DNA restriction enzymes
Online adgang:https://peerj.com/articles/2887.pdf
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