Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.

ICA512 (or IA-2) is a transmembrane protein-tyrosine phosphatase located in secretory granules of neuroendocrine cells. Initially, it was identified as one of the main antigens of autoimmune diabetes. Later, it was found that during insulin secretion, the cytoplasmic domain of ICA512 is cleaved and...

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Автори:	María E Primo, Jean Jakoncic, Martín E Noguera, Valeria A Risso, Laura Sosa, Mauricio P Sica, Michele Solimena, Edgardo Poskus, Mario R Ermácora
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2011-01-01
Серія:	PLoS ONE
Онлайн доступ:	http://europepmc.org/articles/PMC3174154?pdf=render
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