Protective effects of melatonin and naringenin against acitretin induced hepatotoxicity via modulation of oxidative stress and inflammatory signaling
Abstract Drug-induced liver injury (DILI) represents a major clinical challenge, often limiting the therapeutic use of agents such as acitretin, a second-generation retinoid prescribed for psoriasis. This study established and characterized a rat model of acitretin-induced hepatotoxicity, aiming to...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2025-08-01
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| Colección: | Scientific Reports |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1038/s41598-025-16740-9 |
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