Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin

Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative cleavage of heme yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has been attributed to antioxidant defense via the redox cycling system of biliverdin and bilirubin. There is increasing evidence tha...

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Detalhes bibliográficos

Principais autores:	David Stucki, Julia Steinhausen, Philipp Westhoff, Heide Krahl, Dominik Brilhaus, Annika Massenberg, Andreas P. M. Weber, Andreas S. Reichert, Peter Brenneisen, Wilhelm Stahl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-07-01
Colecção:	Antioxidants
Assuntos:	heme heme oxygenase substrate respiratory chain metabolism
Acesso em linha:	https://www.mdpi.com/2076-3921/9/8/652
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