AlCl3 exposure induces nephrotoxicity in mice by mediating ferroptosis through the NRF2 signaling pathway

Aluminum is toxic to both humans and animals. Exposure to AlCl3 can lead to kidney function damage, yet the specific underlying mechanism remains elusive. This study aimed to investigate whether ferroptosis is involved in the renal toxicity induced by AlCl3 exposure in mice and to elucidate its pote...

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Hlavní autoři:	Liu-Dan Liang, Xiao-Yue Zhao, Li Li, Sheng Liang, Jin-Min Zhang, Jian-Nan Lv, Feng-Lian Deng, Chun-Lei Lu, Qian Li, Qi-Wen Huang, Mei-Jin Huang, Hui-Xin Peng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-11-01
Edice:	Frontiers in Toxicology
Témata:	ferroptosis aluminum ferrostatin-1 nephrotoxicity biological toxicity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/ftox.2025.1692410/full
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