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Myosin II isoforms play distinct roles in adherens junction biogenesis

Adherens junction (AJ) assembly under force is essential for many biological processes like epithelial monolayer bending, collective cell migration, cell extrusion and wound healing. The acto-myosin cytoskeleton acts as a major force-generator during the de novo formation and remodeling of AJ. Here,...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mélina L Heuzé, Gautham Hari Narayana Sankara Narayana, Joseph D'Alessandro, Victor Cellerin, Tien Dang, David S Williams, Jan CM Van Hest, Philippe Marcq, René-Marc Mège, Benoit Ladoux
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2019-09-01
Schriftenreihe:eLife
Schlagworte:
mechanobiology
epithelial cells
cytoskeleton
adherens junctions
myosin
Online-Zugang:https://elifesciences.org/articles/46599
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