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P2Y12 receptor as a new target for electroacupuncture relieving comorbidity of visceral pain and depression of inflammatory bowel disease

Abstract Background The P2Y12 receptor is a kind of purinoceptor that is engaged in platelet aggregation, and P2Y12 inhibitors have been used in clinical antithrombotic therapy. The P2Y12 receptor in microglia induces interleukin-1β (IL-1β) expression, which is a key mediator of depression in the br...

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Autors principals: Yanzhen Li, Hong Zhang, Jingwen Yang, Muouyang Zhan, Xuefei Hu, Yongmin Liu, Lingling Yu, Xiaochen Yan, Shangdong Liang, Ruyue Zhang, Ying Lu, Beining Li, Cunzhi Liu, Man Li
Format: Artigo
Idioma:Inglês
Publicat: BMC 2021-12-01
Col·lecció:Chinese Medicine
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Accés en línia:https://doi.org/10.1186/s13020-021-00553-9
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