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Encapsulation of a drug into electrospun fibers spun from water soluble polymers to control solubility and release

Electrospun fibers prepared from water-soluble polymers (PVP, PVA, and HPMC) were loaded with pregabalin, a BCS I drug, to address its fast release and adverse effects. The drug dissolved partially (1.8–2.8 wt%) in the polymers, with excess pregabalin in crystalline form within the fibers. The solub...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lan Yi, Lemeng Shi, János Móczó, Béla Pukánszky
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2024-10-01
Sarja:Heliyon
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Linkit:http://www.sciencedirect.com/science/article/pii/S2405844024149663
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