C-reactive protein conformations and their association with the IL-1β/IL-6 pathway in ocular inflammatory conditions

IntroductionC-reactive protein (CRP) plays a critical role in the innate immune system and serves as a biomarker for various inflammatory conditions. CRP is a dynamic protein undergoing conformational changes between pentameric (pCRP) and monomeric (mCRP) conformations. pCRP is the well-established...

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Principais autores:	Mercedes S. Nabaes Jodar, Víctor Llorenç, Marc Figueras-Roca, Maite Sainz de-la-Maza, Alfredo Adán, Blanca Molins
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-05-01
coleção:	Frontiers in Immunology
Assuntos:	C-reactive protein (CRP) interleukin-1β (IL-1β) interleukin-6 (IL-6) ocular inflammation uveitis diabetic macular edema
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1601145/full
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