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Randomised controlled trials may underestimate drug effects: balanced placebo trial design.

<h4>Background</h4>It is an inherent assumption in randomised controlled trials that the drug effect can be estimated by subtracting the response during placebo from the response during active drug treatment.<h4>Objective</h4>To test the assumption of additivity. The primary hypothesis was that the...

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Detalhes bibliográficos
Principais autores: Karen Lund, Lene Vase, Gitte L Petersen, Troels S Jensen, Nanna B Finnerup
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24416197/?tool=EBI
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