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Re-establishing immune tolerance in multiple sclerosis: focusing on novel mechanisms of mesenchymal stem cell regulation of Th17/Treg balance

Abstract The T-helper 17 (Th17) cell and regulatory T cell (Treg) axis plays a crucial role in the development of multiple sclerosis (MS), which is regarded as an immune imbalance between pro-inflammatory cytokines and the maintenance of immune tolerance. Mesenchymal stem cell (MSC)-mediated therapi...

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Autori principali: Huiru Hu, Hui Li, Ruoyu Li, Peidong Liu, Hongbo Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-07-01
Serie:Journal of Translational Medicine
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Accesso online:https://doi.org/10.1186/s12967-024-05450-x
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