Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury

Objective: Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Although tubular metabolism changes markedly following acute kidney injury (AKI), it remains unclear which metabolic alterations are beneficial or...

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Detalhes bibliográficos

Principais autores:	Adam J. Rauckhorst, Gabriela Vasquez Martinez, Gabriel Mayoral Andrade, Hsiang Wen, Ji Young Kim, Aaron Simoni, Claudia Robles-Planells, Kranti A. Mapuskar, Prerna Rastogi, Emily J. Steinbach, Michael L. McCormick, Bryan G. Allen, Navjot S. Pabla, Ashley R. Jackson, Mitchell C. Coleman, Douglas R. Spitz, Eric B. Taylor, Diana Zepeda-Orozco
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Molecular Metabolism
Assuntos:	Acute kidney injury Hormesis Metabolomics Mitochondrial metabolism Oxidative stress
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2212877823001837
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