TIR-domain-containing protein C as modulator of innate immune checkpoints
Abstract The TIR-domain-containing protein C (TcpC), a virulence factor of the uropathogenic Escherichia coli strain CFT073, binds to crucial components of the toll-like receptor-signaling cascade and the NLRP3 inflammasome thus manipulating these innate immune checkpoints and their immune responses...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Portfolio
2025-11-01
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| Collection: | Scientific Reports |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1038/s41598-025-29677-w |
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