Epigenetic co-regulator HCF-1 promotes lung cancer via O-GlcNAcylation-dependent pathways

The rise in the incidences of lung cancer currently poses a global health challenge, making it crucial to understand the underlying molecular and cellular mechanisms. Host cell factor-1 (HCF-1), a conserved epigenetic transcriptional co-regulator, undergoes proteolytic maturation and glycosylation b...

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Hlavní autoři:	Priyanka P. Srivastava, Abhilash Dasari, Saran Kumar, Ishaan Gupta, Deepali Jain, Shilpi Minocha
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-12-01
Edice:	Molecular Therapy: Oncology
Témata:	MT: Regular Issue lung cancer NSCLC HCF-1 Nkx2.1 O-GlcNAcylation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2950329925001158
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