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A case for improved assessment of gut permeability: a meta-analysis quantifying the lactulose:mannitol ratio in coeliac and Crohn’s disease

Abstract Background A widely used method in assessing small bowel permeability is the lactulose:mannitol test, where the lactulose:mannitol ratio (LMR) is measured. However, there is discrepancy in how the test is conducted and in the values of LMR obtained across studies. This meta-analysis aims to...

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Principais autores: Jonathan Gan, Scarlet Nazarian, Julian Teare, Ara Darzi, Hutan Ashrafian, Alex J. Thompson
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-01-01
Serier:BMC Gastroenterology
Fag:
Coeliac
Crohn’s disease
Lactulose Mannitol test
Gut permeability
Online adgang:https://doi.org/10.1186/s12876-021-02082-z
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