Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule

The elimination of smallpox as an endemic disease and the obvious ethical problems with clinical challenge requires the efficacy evaluation of medical countermeasures against smallpox using the FDA Animal Rule. This approach requires the evaluation of antiviral efficacy in an animal model whose infe...

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Detalhes bibliográficos

Principais autores:	Mark R. Perry, Richard Warren, Michael Merchlinsky, Christopher Houchens, James V. Rogers
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-10-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	rabbitpox virus poxvirus rabbit animal model FDA animal rule
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fcimb.2018.00356/full
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