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Distinct RBC alloantibody responses in type 1 interferon-dependent and -independent lupus mouse models

During transfusion of red blood cells (RBCs), recipients are exposed to both ABO and non-ABO ‘minor’ antigens. RBC donor units and recipient RBCs are not routinely matched for non-ABO antigens. Thus, recipients are exposed to many RBC alloantigens that can lead to RBC alloantibody production and sub...

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Principais autores: Kausik Paul, Rosario Hernández-Armengol, June Young Lee, Che-Yu Chang, Tomohiro Shibata, Michifumi Yamashita, Caroline Jefferies, David R. Gibb
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-01-01
coleção:Frontiers in Immunology
Assuntos:
RBC alloimmunization
lupus
MRL-lpr
type 1 interferons
transfusion
autoimmunity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304086/full
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