SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation

Introduction: Dysfunction of the sinoatrial node (SAN) cells causes arrhythmias, and many patients require artificial cardiac pacemaker implantation. However, the mechanism of impaired SAN automaticity remains unknown, and the generation of human SAN cells in vitro may provide a platform for underst...

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Detalhes bibliográficos

Principais autores:	Takayuki Wakimizu, Kumi Morikawa, Kenta Fukumura, Tetsuo Yuki, Takashi Adachi, Yasutaka Kurata, Junichiro Miake, Ichiro Hisatome, Motokazu Tsuneto, Yasuaki Shirayoshi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-12-01
coleção:	Regenerative Therapy
Assuntos:	SHOX2 HCN4 hiPSCs Sinoatrial node
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352320422000694
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