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Early Developmental Exposure to dsRNA Is Critical for Initiating Efficient Nuclear RNAi in C. elegans

RNAi has enabled researchers to study the function of many genes. However, it is not understood why some RNAi experiments succeed while others do not. Here, we show in C. elegans that pharyngeal muscle is resistant to RNAi when initially exposed to double-stranded RNA (dsRNA) by feeding but sensitiv...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Philip K. Shiu, Craig P. Hunter
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2017-03-01
Rangatū:Cell Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124717303194
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