Fenofibrate diminishes the self-renewal and metastasis potentials of oral carcinoma stem cells through NF-κB signaling

Background/Purpose: NF-κB family of transcription factors are the major contributors to malignant tumor progression, maintenance of cancer stemness, and enhancement of chemoresistance. Fenofibrate, a lipid-lowering drug, has been considered as a candidate for repurposing in the treatment of cancer t...

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Auteurs principaux:	Tzu-Rong Su, Cheng-Chia Yu, Shih-Chi Chao, Chun-Chung Huang, Yi-Wen Liao, Pei-Ling Hsieh, Chuan-Hang Yu, Shih-Shen Lin
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2022-10-01
Collection:	Journal of the Formosan Medical Association
Sujets:	Fenofibrate Cancer stem cells Oral squamous cell carcinoma NF-κB
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S0929664622000341
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