Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γ.

Intracellular pathogens including the apicomplexan and opportunistic parasite Toxoplasma gondii profoundly modify their host cells in order to establish infection. We have shown previously that intracellular T. gondii inhibit up-regulation of regulatory and effector functions in murine macrophages (...

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Detalles Bibliográficos

Principais autores:	Christine Lang, Anke Hildebrandt, Franziska Brand, Lennart Opitz, Hassan Dihazi, Carsten G K Lüder
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS Pathogens
Acceso en liña:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22275866/?tool=EBI
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