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T Cell Therapy Targeted on HLA-A02 Restricted HIV Antigen Epitopes: An Open Label Cellular Therapy Trial Using CD8+ T Cell

Objective: To test the safety and efficacy of a T cell therapy de novo targeting HLA-A02 restricted HIV antigen epitopes.Design: This was a prospective open label clinical trial, which enrolled 28 HIV+ participants and 24 of them finished the trial. The study was publicly registered at Chinese Clini...

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Principais autores: Sai Liu, Jianping Sun, Zhen Li, Ling Qin, Guihai Liu, Kang Li, Hao Wu, Tao Dong, Yonghong Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-03-01
coleção:Frontiers in Immunology
Assuntos:
T cells
cellular immunity
antigen epitopes
cellular therapies
HIV
HLA-A02
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00437/full
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