Effect of TraN key residues involved in DNA binding on pIP501 transfer rates in Enterococcus faecalis

Conjugation is a major mechanism that facilitates the exchange of antibiotic resistance genes among bacteria. The broad-host-range Inc18 plasmid pIP501 harbors 15 genes that encode for a type IV secretion system (T4SS). It is a membrane-spanning multiprotein complex formed between conjugating donor...

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Detalhes bibliográficos

Principais autores:	Claudia Michaelis, Tamara M. I. Berger, Kirill Kuhlmann, Rangina Ghulam, Lukas Petrowitsch, Maria Besora Vecino, Bernd Gesslbauer, Tea Pavkov-Keller, Walter Keller, Elisabeth Grohmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-02-01
coleção:	Frontiers in Molecular Biosciences
Assuntos:	type IV secretion system antibiotic resistance conjugative transfer pIP501 Enterococcus faecalis transfer regulator
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmolb.2024.1268647/full
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