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Mendelian randomization reveals causal effect of Hashimoto's thyroiditis on immune thrombocytopenic purpura

Introduction Patients with immune thrombocytopenic purpura (ITP) usually express thyroid antigen-specific antibodies. The purpose of this study was to explore the causal relationship between Hashimoto's thyroiditis (HT) and ITP.Methods A two-sample Mendelian randomization (TSMR) analysis was applied...

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Principais autores: Zhen Yao, Mingzhu Xu, Zijin Wang, Shanglong Feng, Fuquan Zhang, Shengli Xue, Chengsen Cai
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Hematology
Fag:
Mendelian randomization
GWAS
Hashimoto's thyroiditis
Immune thrombocytopenic purpura
Risk gene
Online adgang:https://www.tandfonline.com/doi/10.1080/16078454.2025.2484959
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