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NULISA: a proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing

Abstract The blood proteome holds great promise for precision medicine but poses substantial challenges due to the low abundance of most plasma proteins and the vast dynamic range of the plasma proteome. Here we address these challenges with NUcleic acid Linked Immuno-Sandwich Assay (NULISA™), which...

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Auteurs principaux: Wei Feng, Joanne C. Beer, Qinyu Hao, Ishara S. Ariyapala, Aparna Sahajan, Andrei Komarov, Katie Cha, Mason Moua, Xiaolei Qiu, Xiaomei Xu, Shweta Iyengar, Thu Yoshimura, Rajini Nagaraj, Li Wang, Ming Yu, Kate Engel, Lucas Zhen, Wen Xue, Chen-jung Lee, Chan Ho Park, Cheng Peng, Kaiyuan Zhang, Adrian Grzybowski, Johnnie Hahm, Susanne V. Schmidt, Alexandru Odainic, Jasper Spitzer, Kasun Buddika, Dwight Kuo, Lei Fang, Bingqing Zhang, Steve Chen, Eicke Latz, Yiyuan Yin, Yuling Luo, Xiao-Jun Ma
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2023-11-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-023-42834-x
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