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The receptor binding properties of H5Ny influenza A viruses have evolved to bind to avian-type mucin-like O-glycans.

Highly pathogenic H5Ny influenza A viruses are causing unprecedented, season-independent outbreaks across avian and mammalian species, including dairy cattle, a novel reservoir. The sialoside-binding properties of influenza A hemagglutinin (HA) are strongly related to its ability to infect and trans...

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Autores principales: Julia Weber, Niels L D Ponse, Xueyong Zhu, María Ríos Carrasco, Alvin X Han, Mathis Funk, Ting-Hui Lin, Alba Gabarroca García, Cindy M Spruit, Ding Zhang, Wenli Yu, Ian A Wilson, Mathilde Richard, Geert-Jan Boons, Robert P de Vries
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2026-01-01
Colección:PLoS Pathogens
Acceso en línea:https://doi.org/10.1371/journal.ppat.1013812
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